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A pilot study of patients with blepharitis treated with omega-3 in the triglyceride form showed that oral treatment resulted in a change in the meibum composition. Furthermore, symptoms, osmolarity, tear break-up time, and blood saturation of omega-3 also improved. This study is in contrast to that of Wojtowicz et. al and Mascai who found no quantifiable change in meibum. One possible explanation for this is the use of omega-3 in the triglyceride form from marine sources rather that omega-3 in the ethyl ester form or alphalinoleic acid which is found in flax seed oil.